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Syntegon (formerly Bosch Packaging Technology) presents new solutions for lab-scale and small batch filling of solid and liquid pharmaceuticals. “The need for smaller quantities of highly potent drugs is rising continuously. We have put these solutions in the focus of our current development activities and are proud to offer our customers a number of exciting new technologies”, says Thomas Mauritzen, General Manager at Syntegon Minneapolis. Both the new GKF 60 capule filling machine and the Versynta Flexible Filling Platform (FFP) make their first live appearance at booth 3139 from October 19 to 21, 2021. They are complemented by a comprehensive portfolio of services and new digital solutions.
GKF 60: new standards in capsule filling for laboratories
The new GKF 60 capsule filling machine enables the development of new formulations with a wide variety of dosing systems at different OEB levels and with an optional 100 percent gravimetric weighing system. The mobile machine with only six stations requires little space and few format parts. Familiar dosing modules for DPI, pellets, tablets, or liquids, as well as the mini-bowl station for scale-up to the next larger production machine offer the highest flexibility. Moreover, the newly developed piezo dosing station makes it possible to accurately fill very small quantities starting at 0.1 milligram filling weight. Customers can choose between a standard, a containment and a combi solution. The latter can be adapted for both simple and highly potent formulations up to OEB5 high-containment in just a few steps.
Versynta FFP: modular small batch solution for liquid pharmaceuticals
Another innovation, which was developed for highly potent pharmaceuticals, is Syntegon’s Versynta FFP. The modular and individually configurable small batch solution for liquid pharmaceuticals with an integrated isolator achieves precise product yields at low output. The platform is based on pre-developed and tested modules that can be flexibly combined. It handles different container types such as vials, syringes, and cartridges, and can be converted to different filling systems including single-use solutions. The Pharma Handling Unit, a four-axis robot developed by Syntegon, allows for safe and gentle transport without glass-to-glass contact. Versynta FFP processes up to 3,600 containers per hour and comes with 100 percent in-process control.
Pharmaceutical competence from formulation to filling
Visitors to booth 3139 have the opportunity to discuss their current and future projects with the Syntegon experts. Syntegon’s portfolio ranges from single machines to complete solutions for lab-scale to high-speed applications. They include sterilization, freeze drying, filling, closing and inspection equipment for liquid pharmaceuticals, as well as assembly solutions for medical and diagnostic devices. The portfolio further covers all process steps for solid dosage forms such as tablet pressing and coating, capsule filling, and continuous manufacturing solutions. Moreover, Syntegon can rely on 40 years of isolator competence in the U.S.: “We developed barrier systems before they were in fashion”, Thomas Mauritzen says. This fact is further underlined by a new campaign.
Tailored services and digital solutions to meet customers’ needs
The portfolio is completed by a comprehensive consulting and service offering along the entire machine lifecycle. Syntegon’s customized offerings range from sparte parts and field service to stock optimization, modernization and preventive maintenance, as well as remote and data-based services. As of November, all Syntegon machines will be delivered “IoT ready” and provide interfaces for numerous digital solutions. Customers benefit from a holistic concept for generating, processing and analyzing machine data, entering a new level of digitalization.
About Syntegon Technology
Syntegon Technology is a leading global process and packaging technology provider. Formerly the packaging division of the Bosch Group, the company, headquartered in Waiblingen (Germany), has been offering complete solutions for the pharmaceutical and food industries for over 50 years. About 6,000 employees at 30 locations in more than 15 countries generated a total revenue of 1.3 billion euros in 2020. The portfolio of intelligent and sustainable technologies includes stand-alone machines, as well as complete systems and services. Fields of application in the pharmaceutical industry are the production, processing, filling, inspection and packaging of liquid and solid pharmaceuticals (e.g. syringes and capsules). In the food industry, the portfolio includes process technology for confectionery as well as packaging solutions for dry foods (e.g. bars, bakery products and coffee), frozen foods and dairy products.
