End-to-End Multi-Attribute Method Solution Accelerates Biotherapeutic Development and Manufacturing

Biopharmaceutical laboratories working across R&D, manufacturing and quality control (QC) environments can now streamline biopharmaceutical characterization, process monitoring and release testing using a new seamless, built-for-purpose multi-attribute method (MAM) workflow.

The Thermo Scientific MAM 2.0 workflow is a culmination of collaborations and conversations with industry leaders that led to features added specifically to address MAM user needs. The result is an?end-to-end, single vendor solution?providing a holistic ecosystem for implementation from biotherapeutic development through to QC. The MAM 2.0 solution enables direct connectivity in both hardware and software through all stages of development and manufacturing.?

The workflow manages all analytical processes from instrument control to data management through a secure, integrated software ecosystem, streamlining the process from development to QC. The Thermo Scientific BioPharma Finder 5.0 software provides MAM users with fit-for-purpose enhancements for confident attribute characterization, data security and integrity, customizable reporting, and team collaboration at a global scale. From instrument control, to data storage and processing, through to result generation, Thermo Scientific Chromeleon Chromatography Data System 7.3.1 software manages the analytical processes and enables a simple transfer of the entire MAM workflow from development to QC.

Laboratories will benefit from a consistent technology platform between the Thermo Scientific Orbitrap Exploris 240 mass spectrometer in development and the new Thermo Scientific Orbitrap Exploris MX mass detector, specifically designed for QC applications. Both solutions together will future proof customer needs and enable consistent unit-to-unit performance, while continuing to offer the power of Orbitrap technology. Furthermore, MAM 2.0 includes training, on-going support, and relationships with laboratories to bring their next biotherapeutic candidate straight through to breakthrough.

Laboratories will benefit from a consistent technology platform between the Thermo Scientific Orbitrap Exploris 240 mass spectrometer in development and the new Thermo Scientific Orbitrap Exploris MX mass detector, specifically designed for QC applications. Both solutions together will future proof customer needs and enable consistent unit-to-unit performance, while continuing to offer the power of Orbitrap techn