Astellas Announces Abstracts Highlighting Growing Oncology Portfolio to be Presented at 2018 American Society of Clinical Oncology (ASCO) Annual Meeting

Astellas Pharma Inc announced hat a wide selection of abstracts highlighting the Company’s diverse oncology portfolio across a broad range of cancers have been accepted for oral and poster presentation at the 2018 American Society of Clinical Oncology (ASCO) Annual Meeting, June 1-5 in Chicago.

Highlights of the data and studies being presented include findings for: men with non-metastatic Castration-Resistant Prostate Cancer (CRPC) taking enzalutamide* and androgen deprivation therapy; patients with locally advanced or metastatic urothelial cancer taking enfortumab vedotin**, an investigational antibody-drug conjugate (ADC); and patients taking gilteritinib in Phase 3 trial in FLT3 mutation-positive (FLT3mut+) acute myeloid leukemia (AML).

“The Astellas abstracts accepted for presentation at this year’s ASCO meeting demonstrate the depth and breadth of our growing leadership in oncology across a broad range of cancers,” said Steven Benner, M.D., senior vice president and global therapeutic area head, Oncology Development, Astellas. “These data demonstrate the strength and progress of our oncology pipeline driven by investment in R&D and collaborative partnerships.”

The following will be presented during an oral presentation:

Title: (Abstract 4504) Updated Results from the enfortumab vedotin Phase 1 (EV-101) Study in Patients with Metastatic Urothelial Cancer (mUC)

Presenter: Jonathan E. Rosenberg, MD

    Session Date/Time:  June 3, 9:12 AM – 9:24 AM CDT
    Oral Abstract Session: Genitourinary (Nonprostate) Cancer
    Location: Arie Crown Theater

Additionally, the following data will be shared during poster presentations:

Title: (Abstract TPS4590) EV-201 Study: A Single-Arm, Open-Label, Multicenter Study of enfortumab vedotin for Treatment of Patients with Locally Advanced or Metastatic Urothelial Cancer who previously Received Immune Checkpoint Inhibitor Therapy

Presenter: Jonathan E. Rosenberg, MD

    Session Date/Time: June 2, 8:00 AM – 11:30 AM CDT
    Poster Session: Genitourinary (Nonprostate) Cancer
    Location: Hall A

Title: (Abstract 5010) Health-Related Quality of Life (HRQoL) Deterioration and Pain Progression in Men with Non-Metastatic Castration-Resistant Prostate Cancer (M0-CRPC): Results from the PROSPER study

Presenter: Gerhardt Attard, MD, PhD

    Session Date/Time: June 2, 1:15 PM – 4:45 PM CDT
    Poster Session: Genitourinary (Prostate) Cancer
    Location: Hall A
    Poster Discussion Session on June 2, 2018, 4:45 PM – 6:00 PM CDT, at S406

Title: (Abstract 5043) Association Between Health-Related Quality of Life (HRQoL) and clinical outcomes in non-metastatic castration-resistant prostate cancer (M0 CRPC): Results from the PROSPER study

Presenter: Gerhardt Attard, MD, PhD

    Session Date/Time: June 2,1:15 PM – 4:45 PM CDT
    Poster Session: Genitourinary (Prostate) Cancer
    Location: Hall A

Title: (Abstract TPS7075) A Phase 3, Trial of Gilteritinib, as Maintenance Therapy after Allogeneic Hematopoietic Stem Cell Transplantation in Patients with FLT3-ITD + AML

Presenter: Mark J. Levis, MD, PhD

    Session Date/Time: June 4, 8:00 AM – 11:30 AM CDT
    Poster Session: Hematologic Malignancies—Leukemia, Myelodysplastic Syndromes, and Allotransplant
    Location: Hall A

*Enzalutamide is developed through a collaboration between Pfizer and Astellas and commercialized under the brand name XTANDI®.
**Enfortumab vedotin is developed through a collaboration between Seattle Genetics and Astellas

About Astellas
Astellas Pharma Inc., based in Tokyo, Japan, is a company dedicated to improving the health of people around the world through the provision of innovative and reliable pharmaceutical products. We focus on Urology, Oncology, Immunology, Nephrology and Neuroscience as prioritized therapeutic areas while advancing new therapeutic areas and discovery research leveraging new technologies/modalities. We are also creating new value by combining internal capabilities and external expertise in the medical/healthcare business. Astellas is on the forefront of healthcare change to turn innovative science into value for patients. For more information, please visit our website at www.astellas.com/en