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Clinical Trials

QR Pharma receives FDA clearance to conduct clinical trials with its second novel Alzheimer compound

  QR Pharma, Inc., a developer of novel drugs to treat Alzheimer's disease (AD), announced today that the United States Food and Drug Administration (FDA) has accepted the Investigational New Drug application (IND) to begin human clinical trials and...

Bayer and Regeneron Report Positive Top-Line Results of Two Phase 3 Studies

Bayer HealthCare and Regeneron Pharmaceuticals, Inc. announced that in two parallel Phase 3 studies in patients with the neovascular form of age-related macular degeneration (wet AMD), all regimens of VEGF Trap-Eye (aflibercept ophthalmic solution), including VEGF Trap-Eye dosed every...

Reata and Abbott Announce Positive Phase 2b Study Results for Bardoxolone Methyl

Abbott Park, Illinois-Reata Pharmaceuticals and Abbott today announced data from a Phase 2b study which suggests that bardoxolone methyl, an investigational treatment for chronic kidney disease (CKD), may reduce the stage of CKD and improve estimated glomerular filtration rate...

Novartis discontinues ASA404 clinical trial program and shifts focus to other cancer compounds in early and late stage development

Novartis announced that the clinical trial program for the investigational cancer treatment ASA404 (vadimezan) will be discontinued and resources will be reallocated to other compounds in the oncology pipeline. The decision was made after interim results from a Phase...

Genentech announced the result of Phase II clinical trail of RG7204

Genentech, Inc., a member of the Roche Group announced results from a Phase II clinical study of RG7204 (PLX4032), an investigational first-in-class molecule designed to selectively inhibit a cancer-causing, mutated form of the BRAF protein found in approximately half...

Sanofi Pasteur’s Dengue Vaccine in Final Stage of Clinical Development

Sanofi Pasteur, the vaccines division of sanofi-aventis Group, announced that its dengue vaccine is in final stage of clinical development. Sanofi Pasteur’s dengue vaccine, the world’s most clinically advanced dengue vaccine candidate1,2, entered its first phase 3 clinical study...

Roche reports promising Phase II results with new targeted approach in advanced melanoma

Roche announced results from a Phase II clinical study of RG7204 PLX4032), an investigational first-in-class molecule designed to selectively inhibit a cancer-causing, mutated form of the BRAF protein found in approximately half of metastatic melanoma tumors. ...

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